Scrofulous
Definition: morally degenerate; corrupt.
“Scrofula” is a form of tuberculosis. Presumably, this is extrapolated to mean disease in general. Also, it sounds like “scruffy,” which fits (though the two words don’t seem to have related origins).
Why I Looked It Up
A novel had a character saying:
On the way back here we stopped at a scrofulous pub and laughed and drank ourselves sick.