Fu Manchu was the villain in a series of Sax Rohmer novels in the first half of the 20th century and continuing into films.
In popular culture, he is considered an archetype of a “supervillain.” Generally depicted as Asian, with a mustache that extends downwards from the corners of his mouth.
(The type of mustache itself has come to be called a “Fu Manchu.”)
The Manchu people are the natives of Manchuria, which provides some basis for his depiction as Asian.